Definition of acetylcholinesterase in English:

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Pronunciation: /əˌsētlˌkōləˈnestəˌrās/ Pronunciation: /əˌsētlˌkōləˈnestəˌrāz/ Pronunciation: /ˌasitlˌkōləˈnestəˌrās/ Pronunciation: /ˌasitlˌkōləˈnestəˌrāz/


An enzyme that causes rapid hydrolysis of acetylcholine. Its action serves to stop excitation of a nerve after transmission of an impulse.
Example sentences
  • An early favorite target was the vital enzyme acetylcholinesterase, required for hydrolysis of acetylcholine at neuromuscular junctions, and it has been exploited by agrochemical companies in a spectacular manner.
  • Once released, ACh must be removed rapidly in order to allow repolarization to take place; this step, hydrolysis, is carried out by the enzyme, acetylcholinesterase.
  • All nerve agents act by inhibiting the enzyme acetylcholinesterase, which breaks down the neurotransmitter acetylcholine.

For editors and proofreaders

Syllabification: a·ce·tyl·cho·lin·es·ter·ase

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