(also adenyl cyclase /ˈadn-il/)
An enzyme that catalyzes the formation of cyclic adenylic acid from adenosine triphosphate.
- The cAMP is produced by adenylate cyclase, and that enzyme is activated by phosphorylated IIA Glc.
- The response of cells to the binding of glucagon to its cell surface receptor is the activation of the enzyme adenylate cyclase which is associated with the receptor.
- When epinephrine contacts a cell membrane, it triggers the allosteric activation of adenylate cyclase, the enzyme that creates cAMP. cAMP then allosterically activates a protein kinase.
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