Share this entry

amphipathic Syllabification: am·phi·path·ic
Pronunciation: /ˌamfəˈpaTHik/

Definition of amphipathic in English:


(Of a molecule, especially a protein) having both hydrophilic and hydrophobic parts.
Example sentences
  • Many peptides and proteins interact strongly with amphiphilic molecules and these interactions are of vast importance, not only in vivo but also in technical applications.
  • This should be taken as an indication that the contributions of the hydrophilic and hydrophobic portions of the amphiphilic molecules to the free energy of interaction with the solvent phases are not independent.
  • In our present paper, we added a spherical nanoparticle interacting attractively with the hydrophilic segments of amphiphilic molecules.


1930s: from amphi- + Greek pathikos (from pathos 'experience').

Definition of amphipathic in:

Share this entry


What do you find interesting about this word or phrase?

Comments that don't adhere to our Community Guidelines may be moderated or removed.

Get more from Oxford Dictionaries

Subscribe to remove ads and access premium resources

Word of the day haughty
Pronunciation: ˈhôdē
arrogantly superior and disdainful