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centromere

Syllabification: cen·tro·mere
Pronunciation: /ˈsentrəˌmir
 
/

Definition of centromere in English:

noun

Biology
The point on a chromosome by which it is attached to a spindle fiber during cell division.
Example sentences
  • In fact, we did not find any informative marker in the three chromosomal divisions around the centromere of this chromosome.
  • The presence of a kinetochore spot indicates the centromere region of each chromosome.
  • We conclude that chromosomes with damaged centromeres fail to correctly attach to the spindle, thus producing MN and monosomy.

Origin

1920s: from Latin centrum (see center) + Greek meros 'part'.

Derivatives

centromeric

1
Pronunciation: /ˌsentrəˈmi(ə)rik, -ˈmerik/
adjective
Example sentences
  • Strains were transformed with a control centromeric plasmid or a centromeric plasmid carrying the wild-type GUK1 gene.
  • In Drosophila, relocation of a euchromatic gene near centromeric or telomeric heterochromatin often leads to its mosaic silencing.
  • In addition, binding of the yeast CBF3 kinetochore complex to centromeric DNA was severely compromised in this mutant.

Definition of centromere in:

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