A synthetic drug used to treat fluid retention and high blood pressure. It is one of the thiazide diuretics.
- Drugs such as alkylating agents, antimetabolites, anticonvulsants, chlorothiazide diuretics and estrogens can inhibit platelet production by suppressing megakaryocyte production. (2,3)
- Thiazide diuretics, such as chlorothiazide and hydrochlorothiazide, may be excreted unchanged in the urine.
- Adding metolazone or chlorothiazide 500 mg IV to furosemide may generate additional diuresis.
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