Definition of cholinesterase in English:

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Pronunciation: /ˌkōləˈnestəˌrās/ /-ˌrāz/


An enzyme, especially acetylcholinesterase, that hydrolyzes esters of choline.
Example sentences
  • Cholinesterase inhibitors, which reduce cholinesterase - the enzyme that breaks down acetylcholine - are the only FDA-approved treatment for Alzheimer's.
  • By inhibiting cholinesterase, more acetylcholine is available for normal memory-related and cognitive functioning.
  • In someone with Alzheimer's, cholinesterase breaks down and destroys acetylcholine, the neurotransmitter chemical.

For editors and proofreaders

Syllabification: cho·lin·es·ter·ase

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