Definition of cholinesterase in English:


Syllabification: cho·lin·es·ter·ase
Pronunciation: /ˌkōləˈnestəˌrās, -ˌrāz


  • An enzyme, especially acetylcholinesterase, that hydrolyzes esters of choline.
    More example sentences
    • Cholinesterase inhibitors, which reduce cholinesterase - the enzyme that breaks down acetylcholine - are the only FDA-approved treatment for Alzheimer's.
    • By inhibiting cholinesterase, more acetylcholine is available for normal memory-related and cognitive functioning.
    • In someone with Alzheimer's, cholinesterase breaks down and destroys acetylcholine, the neurotransmitter chemical.

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