Definition of circularize in English:

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Pronunciation: /ˈsərkyələˌrīz/


[with object]
1Distribute a large number of letters, leaflets, or questionnaires to (a group of people) in order to advertise something or canvas opinion.
Example sentences
  • Companies, firms, businesses and individuals have been circularised and may contact any of the following regarding sponsorship and/or entries.
  • They only realised the full implications of the story when they were forwarded the e-mail that had been circularised to the national media.
  • Some customers locally have been given notice of the impending closure, but not all houses appear to have been circularised as yet.
2 Biochemistry Make (a stretch of DNA) into a circular loop.
Example sentences
  • The plasmid DNA was then circularized with ligase and used to transform E. coli.
  • Upon injection into the cell, the cohesive ends anneal and are ligated, circularizing the chromosome.
  • The digested DNA was circularized by self-ligation.



Pronunciation: /ˌsərkyələrəˈzāSHən/
Example sentences
  • Ira provided a very convincing argument that, after infection, late gene expression must require circularization of the injected DNA.
  • A large pool of DNA sequences was investigated by different authors, and their propensity to circularization was experimentally determined and predicted by theoretical approaches.
  • Direct evidence for RNA circularization is shown in this illustration.

For editors and proofreaders

Syllabification: cir·cu·lar·ize

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