Definition of de novo in English:

de novo

Syllabification: de no·vo
Pronunciation: /dā ˈnōvō, di

adverb& adjective

Starting from the beginning; anew: [as adverb]: in a pure meritocracy, everyone must begin de novo [as adjective]: a general strategy for de novo protein design
More example sentences
  • Both the Federal Reserve and the Office of the Comptroller of the Currency recommend that Congress remove outdated barriers to de novo interstate branching.


early 17th century: Latin, literally 'from new'.

Definition of de novo in: