The ratio of a particular allele to the total of all other alleles of the same gene in a given population.
- This study included only male blood donors, whereas our study included a large population of male and female subjects, which may give a better representation of the gene frequency in the overall population.
- In addition to its effects on allelic frequencies within populations, natural selection is expected to affect the extent of divergence in gene frequency between populations.
- Evolution itself has come to be defined as a change in gene frequency in a population.
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