Entry from British & World English dictionary
The switching off of the expression of a gene, for example by the introduction of an antisense RNA that blocks translation of the messenger RNA.
- Such mutants have been generated by chemical mutagenesis, gene disruption, and antisense gene silencing.
- This outcome is in contrast to that with sex-specific differences in selection, which can cause extreme differences in gene expression and even gene silencing.
- The organization of DNA into euchromatin and heterochromatin is implicated in gene silencing.
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