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histamine Syllabification: his·ta·mine
Pronunciation: /ˈhistəˌmēn/

Definition of histamine in English:


A compound that is released by cells in response to injury and in allergic and inflammatory reactions, causing contraction of smooth muscle and dilation of capillaries.
Example sentences
  • The allergic reaction causes the cells to release histamine, a chemical which prompts the sneezing and itching impulse.
  • Quercetin reduces histamine degranulation and the subsequent release of histamine and inflammatory leukotrienes.
  • Allergic reactions involve the release of histamine, a chemical that triggers inflammation and swelling.


Pronunciation: /ˌhistəˈminik/
Example sentences
  • This drug has minimal activity at histaminic, serotonergic, cholinergic or adrenergic receptor sites.
  • Antipsychotics with lower potency have a greater affinity for histaminic, alpha-adrenergic and muscarinic receptors.
  • Depending on the specific drug, there may be effects on muscarinic, adrenergic, or histaminic receptors.


Early 20th century: blend of histidine and amine.

Definition of histamine in:
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