Definition of histone in English:


Syllabification: his·tone
Pronunciation: /ˈhiˌstōn


  • Any of a group of basic proteins found in chromatin.
    More example sentences
    • Indeed, chromatin is known to be rich not only in histones but also HMG proteins, which may play a role in this charge shielding.
    • Both nonhistone proteins and histones form complexes with TP.
    • People solve this packing problem by tightly wrapping their DNA around proteins called histones.


late 19th century: coined in German, perhaps from Greek histanai 'arrest' or from histos 'web, tissue'.

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