Definition of homozygote in English:

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homozygote

Pronunciation: /ˌhōməˈzīɡōt/
/ˌhäməˈzīɡōt/

noun

Genetics
An individual having two identical alleles of a particular gene or genes and so breeding true for the corresponding characteristic. Compare with heterozygote.
Example sentences
  • This is because inbred individuals are more likely to express deleterious alleles as homozygotes than are outbreds.
  • Similarly, inbreeding decreases the effective size of selection but unmasks deleterious alleles in homozygotes.
  • Expression in heterozygotes and homozygotes is apparently identical.

Derivatives

homozygosity

Pronunciation: /-zīˈɡäsitē/
noun
Example sentences
  • This was considered an appropriate technique since there was a high incidence of homozygosity and single-site heterozygosity.
  • Increased individual homozygosity and decreased population-wide genetic diversity should be disadvantageous.
  • For partially recessive mutations, high levels of homozygosity in inbred populations may partially oppose these effects.

homozygous

Pronunciation: /ˌhōməˈzīɡəs/
/ˌhäməˈzīɡəs/
adjective
Example sentences
  • In human patients, homozygous as well as heterozygous mutations are associated with disease.
  • Thirteen animals were heterozygous while one was homozygous for this amino acid substitution.
  • Because of perpetual inbreeding, each of the strains has an essentially homozygous genome.
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