A substance found in St. John’s wort, credited with chemical and pharmacological properties similar to those of antidepressants.
- St.John's Wort contains hypericin, which inhibits monoamine oxidase, a chemical associated with depression.
- The antitumor properties of St. John's wort are attributed to hypericin, which is a powerful photosensitizer.
- Today, St. John's wort standardized to 0.3% hypericin easily outsells its pharmaceutical rival, Prozac, and its derivatives.
Early 20th century: from hypericum 'a yellow-flowered plant' + -in, chemical suffix.
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