Definition of inoculate in English:

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Pronunciation: /iˈnäkyəˌlāt/


[with object]
1Treat (a person or animal) with a vaccine to produce immunity against a disease: he inoculated his tenants against smallpox Compare with vaccinate.
More example sentences
  • Troops were inoculated against expected infectious diseases as well as two agents of biological warfare - anthrax and botulinum toxin.
  • Army doctors have started inoculating villagers against disease.
  • I'll rest easier knowing I'm inoculated against eradicated diseases like Smallpox.
1.1Introduce (an infective agent) into an organism: it can be inoculated into laboratory animals
More example sentences
  • In lymphatic filariasis, infective larvae are inoculated by mosquitoes; adult worms are found in lymph nodes or adjacent lymphatics, and offspring circulate in the blood, often only at night.
  • Given their effects on soybean plants, it is hypothesized that the PGPR strains exert their influence via the production of specific compounds after they have been inoculated into plant rhizospheres.
  • Organisms obtained from these animals, when inoculated into uninfected animals, proved to be unresponsive to atovaquone therapy, suggesting the emergence of drug resistance.
1.2Introduce (cells or organisms) into a culture medium.
Example sentences
  • For initial qualitative screening of elevated mutation frequencies in isolates, a single colony of each isolate to be tested was inoculated into 4 ml Luria broth.
  • A purified colony was inoculated into 5 ml of broth and grown overnight before plating dilutions onto LB plates supplemented with 50 g/ml thymidine.
  • White colonies were inoculated into 96-well plates.



Pronunciation: /iˈnäkyələb(ə)l/
Example sentences
  • The article covers a probable impact of global changes on the distribution of bloodsucking arthropods as the vectors of inoculable disease agents.
  • In England, the increase of inoculable diseases was 20 per cent., notwithstanding an expenditure of 200 millions sterling since 1850 in sanitary works.


Pronunciation: /iˈnäkyəˌlādər/
Example sentences
  • Mick had left a skilled job as a juvenile-salmon inoculator.
  • In that great day there won't be any doctors anymore, nothing but inoculators - and here and there a perishing undertaker.
  • Money allowed them to purchase the services of inoculators.


Late Middle English (in the sense 'graft a bud or shoot into a plant of a different type'): from Latin inoculat- 'engrafted', from the verb inoculare, from in- 'into' + oculus 'eye, bud'. The sense 'vaccinate' dates from the early 18th century.

  • Originally inoculation was a task of gardeners rather than of doctors and nurses. To inoculate something was to graft a bud or shoot into a plant of a different type. This corresponds to its Latin source inoculare ‘to graft’, from in- ‘into’ and oculus ‘eye, bud’ (as in binocular (early 18th century) and ocular (late 16th century)). The horticultural sense dates from the late Middle Ages. As a medical procedure people could inoculate a person from the early 18th century—its first uses referred to the treatment of smallpox. See also vaccine

Words that rhyme with inoculate


For editors and proofreaders

Syllabification: in·oc·u·late

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