Modifying the force or speed of contraction of muscles.
- A direct positive inotropic effect and an increase in the refractory period also have been postulated as possible antiarrhythmia mechanisms of spironolactone.
- It has therapeutic use in congestive heart failure and edema, having a positive inotropic effect on cardiac muscle.
- It seems that the capability for carefully manipulating and combining agents for use in both inotropic and vasodilator actions has improved our ability to manage previously refractory patients.
Definition of inotropic in:
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