A mouse whose DNA has been genetically engineered so that it does not express particular proteins.
- Postdoctoral fellow Deborah Burks, lead author of the Nature paper, decided to examine fertility in the knockout mice.
- Liver regeneration is impaired in iNOS gene knockout mice.
- More importantly, researchers can use knockout mice to develop better models of many inherited human diseases.
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Syllabification: knock·out mouse
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