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light chain

Syllabification: light chain

Definition of light chain in English:

noun

Biochemistry
A protein subunit that, as one of a pair, forms part of the main antigen-binding region of an immunoglobulin molecule.
Example sentences
  • Free kappa and lambda light chains are antibody fragments secreted by plasma cells in the bone marrow.
  • The complete dissociation of all of the regulatory light chains was a precondition of later experiments.
  • This assay is highly sensitive to increasing concentrations of monoclonal free kappa or free lambda light chains in the serum of patients with evolving or relapsing myelomas.

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