Definition of mitogen in English:

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mitogen

Pronunciation: /ˈmīdəjən/

noun

Physiology
A substance that induces or stimulates mitosis.
Example sentences
  • Platelet-derived growth factor is a major polypeptide growth factor found in human serum, platelets and fibroblasts and is a potent mitogen for cells of mesenchymal origin.
  • The technique of three-color flow cytometry was used to generate precise estimates of cytokine responses to cells collected from the blood, cultured and stimulated with a mitogen.
  • Cells from each individual were tested at 3 different concentrations of the mitogens for optimum stimulation.

Derivatives

mitogenic

Pronunciation: /ˌmītəˈjenik/
adjective
Example sentences
  • In addition, muscarinic receptor stimulation augmented the mitogenic responses of human airway smooth muscle cells to epidermal growth factor.
  • Endothelin - 1 has been implicated in pulmonary hypertension because of its dual vasoconstrictor and mitogenic actions.
  • When associated with vesicles of dipalmitoylphosphatidylcholine, surfactant protein C inhibited the mitogenic effect of lipopolysaccharide to a macrophage cell line.

Origin

1960s: from mitosis + -gen.

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