Definition of neostigmine in English:


Syllabification: ne·o·stig·mine
Pronunciation: /ˌnēōˈstigmēn


  • A synthetic compound that inhibits cholinesterase and is used to treat ileus, glaucoma, and myasthenia gravis.
    More example sentences
    • At the end of procedures, the neuromuscular blockade was reversed, if necessary, with neostigmine, 0.03 mg/kg, and atropine, 0.015 mg/kg.
    • The study was terminated with the administration of atropine and neostigmine to reverse muscle paralysis.
    • The use of neostigmine to antagonise neuromuscular blockade may increase bowel motility and result in a higher rate of anastomotic leakage.


1940s: from neo- 'new', on the pattern of physostigmine.

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