An opening, as of a pipe or tube, or one in the body, such as a nostril or the anus.
- On the left there was an obstructing lesion noted at the orifice of the left upper lobe bronchus.
- Jordan's hands clasped over the inhaler and pressed the orifice of it and faced it to her mouth.
- The ureteral orifices are located at the proximal borders of the trigone area.
Late Middle English: from French, from late Latin orificium, from os, or- 'mouth' + facere 'make'.
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