Any of a set of viruses pathological in humans and animals that includes the cowpox, smallpox, and monkeypox viruses.
- GenusOrthopoxvirus, family Poxviridae.
- The disease is caused by Monkeypox virus, which belongs to the orthopoxvirus group of viruses.
- Guidelines for vaccination of laboratory personnel who directly handle orthopoxviruses have not changed.
- Smallpox is an orthopoxvirus, was certified as eradicated in 1980, and no longer occurs naturally.
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