Definition of penicillinase in English:

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penicillinase

Pronunciation: /ˌpenəˈsilənās/

noun

Biochemistry
An enzyme that can inactivate penicillin, produced by certain bacteria.
Example sentences
  • For example, the resistance to penicillin initially was due to production of an enzyme penicillinase by bacteria, antibiotics like cloxallin were developed which was resistant to penicillinase enzyme.
  • A control gene regulates the production of an enzyme that destroys the antibiotic, e.g. penicillinase which destroys penicillin.
  • Penicillin was first used in the early 1940s and by 1950, most Staphylococcus aureus organisms were resistant to the drug by virtue of elaboration of a penicillinase enzyme.
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