Definition of perforin in English:

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Pronunciation: /ˈpərfərən/


A protein, released by killer cells of the immune system, that destroys targeted cells by creating lesions like pores in their membranes.
Example sentences
  • The CD8 cells of long-term nonprogressors produce more perforin than do CD8 cells of HIV-positive people who developed AIDS, the scientists found.


1980s: from the verb perforate + -in1.

For editors and proofreaders

Syllabification: per·fo·rin

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