Entry from British & World English dictionary
noun[mass noun] Genetics
A reversal of the normal order of genes in a chromosome segment involving parts of a chromosome at both sides of the centromere.
- There is no doubt, however, on the occurrence of a pericentric inversion that brought the centromere inside the chromosome, with one breakpoint occurring between markers C and D.
- Despite the presence of a pericentric inversion of chromosome 2, fertile offspring are produced by interbreeding of the different subspecies in captive conditions.
- This method can be applied to mitochondrial genomes, to X chromosomes, and to chromosome arms of species of genera Drosophila and Anopheles, where pericentric inversions and translocations are rare.
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