Definition of pharmacophore in English:

Share this entry

pharmacophore

Pronunciation: /ˈfärməkəˌfôr/

noun

A part of a molecular structure that is responsible for a particular biological or pharmacological interaction that it undergoes.
Example sentences
  • This pharmacophore identifies two important hydrogen-bonding interactions at opposite ends of the ligand.
  • The phenothiazine ring is a well-known pharmacophore, and chlorpromazine is a prototype of this class of antipsychotic drugs.
  • The similar mechanism of action of paclitaxel, the epothilones, discodermolide and eleutherobin has led to the suggestion that these structurally dissimilar substances possess common pharmacophores.

For editors and proofreaders

Syllabification: phar·ma·co·phore

Share this entry
 

What do you find interesting about this word or phrase?

Comments that don't adhere to our Community Guidelines may be moderated or removed.