A bitter compound used to stimulate the respiratory and nervous systems, especially in treating barbiturate poisoning.
- When the synapses of these inhibitory neurons are blocked by drugs (such as of picrotoxin or penicillin), the excitatory network can sustain a chain reaction leading to an epileptiform discharge.
- The only synaptic feedback to the pyloric pacemaker group through the EP to PD inhibitory synapse was removed by applying 10-5 M picrotoxin in the bath.
- Picrotoxin eliminates frequency selectivity of an auditory interneuron in a bushcricket.
Mid 19th century: from Greek pikros 'bitter' + toxin.
Definition of picrotoxin in:
What do you find interesting about this word or phrase?
Comments that don't adhere to our Community Guidelines may be moderated or removed.