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1an ornamental tablet, typically of metal, porcelain, or wood, that is fixed to a wall or other surface in commemoration of a person or event. 2a sticky deposit on teeth in which bacteria proliferate. 3 Medicine a small, distinct, typically raised patch or region resulting from local damage or deposition of material, such as a fatty deposit on an artery wall in atherosclerosis or a site of localized damage of brain tissue in Alzheimer’s disease. Microbiology a clear area in a cell culture caused by the inhibition of growth or destruction of cells by an agent such as a virus.