Share this entry
proband Syllabification: pro·band
Pronunciation: /ˈprōˌband/ /prōˈband/

Definition of proband in English:


A person serving as the starting point for the genetic study of a family (used especially in medicine and psychiatry).
Example sentences
  • Furthermore, all these approaches are unable to handle trios with missing genotypic information on the proband and these families are typically excluded from the analysis.
  • A genetic basis to the disorder is borne out by risk increasing with genetic proximity to the proband.
  • Most data sets utilized in the study of hereditary diseases are constructed around probands, making correction for ascertainment bias necessary; this set of data is no exception.


1920s: from Latin probandus 'to be proved', gerundive of probare 'to test'.

Definition of proband in:
Share this entry

What do you find interesting about this word or phrase?

Comments that don't adhere to our Community Guidelines may be moderated or removed.

Subscribe to remove ads and access premium resources