Definition of probenecid in English:


Syllabification: pro·ben·e·cid
Pronunciation: /prōˈbenəsid


A synthetic compound that promotes increased excretion of uric acid and is used to treat gout.
More example sentences
  • There are two classes of drugs to reduce uric acid: uricosurics, such as probenecid, which increases excretion, and xanthine oxidase inhibitors, such as allopurinol, which reduce production.
  • Parenteral treatment refused: amoxycillin 500 mg four times a day plus probenecid 500 mg four times a day for 14 days
  • Administration of this drug with probenecid should be avoided as it has been found to inhibit the renal excretion of meropenem.


1950s: from pro(pyl) + ben(zoic) + -e- + (a)cid.

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cause (someone) to lose confidence or hope; dispirit