Definition of procoagulant in English:


Syllabification: pro·co·ag·u·lant
Pronunciation: /ˌprōkōˈagyələnt


  • Relating to or denoting substances that promote the conversion in the blood of the inactive protein prothrombin to the clotting enzyme thrombin.
    More example sentences
    • Protective mechanisms prevent thrombin and other procoagulant enzymes from forming in healthy intact blood vessels.
    • Thrombomodulin is an integral membrane glycoprotein that binds thrombin changing it from a procoagulant protein to an anticoagulant.
    • The cap acts as a protective barrier between circulating blood and the thrombogenic, procoagulant contents of the lesion.


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  • A procoagulant substance.
    More example sentences
    • Taipan venom is overwhelmingly neurotoxic, including pre and post-synaptic neurotoxins, as well as powerful procoagulants and myolysins.
    • The exudate, procoagulants, and leukocytes form casts in the airways, resulting in poor gas exchange.
    • Chemotherapy acts by killing leukemic cells, which release procoagulants that can produce disseminated intravascular coagulation.

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