Definition of protonate in English:

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Pronunciation: /ˈprōtnˌāt/


[with object] Chemistry
Transfer a proton to (a molecule, group, or atom), so that a coordinate bond to the proton is formed.
Example sentences
  • In the second basic photocycle step, the chromophore is protonated and structural changes take place in the protein.
  • All aspartic acid and glutamic acid residues as well as C-terminal groups were deprotonated; arginine, lysine, and N-terminal groups were protonated.
  • We postulate that this pathway is blocked when both groups are protonated (state A) or deprotonated (state C).



Pronunciation: /ˌprōtnˈāSHən/
Example sentences
  • This reaction is initiated by the electrophilic protonation of isobutylene.
  • These reactions, some of which are run on a large scale in the petroleum industry, are initiated by the protonation of saturated hydrocarbons.
  • The protonation of amino acid side chains was supposed to cause the reorganization of the native state into the so-called A-state.

For editors and proofreaders

Syllabification: pro·ton·ate

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