Definition of sclerosis in English:


Syllabification: scle·ro·sis
Pronunciation: /skləˈrōsəs


1Abnormal hardening of body tissue.
More example sentences
  • In MS, myelin is lost in multiple areas, leaving scar tissue called sclerosis.
  • The lymph node biopsy showed sclerosis surrounding cellular nodules that contained clusters of large atypical cells admixed with small lymphocytes and numerous eosinophils.
  • It exhibited squamous differentiation, sclerosis, and eosinophilia.
2Excessive resistance to change: the challenge was to avoid institutional sclerosis
More example sentences
  • In other words, this is a story not about institutional sclerosis, but about the necessarily contingent process of institutional change.


late Middle English (originally denoting a hard external tumor): via medieval Latin from Greek sklērōsis, from sklēroun 'harden'.

Definition of sclerosis in: