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senile plaque

Syllabification: se·nile plaque

Definition of senile plaque in English:

noun

Medicine
A microscopic mass of fragmented and decaying nerve terminals around an amyloid core, numbers of which occur in the brains of people with Alzheimer’s disease.
Example sentences
  • The vaccine induces an immune response specifically against beta-amyloid (the protein that makes up senile plaques in Alzheimer's) and has been shown to reduce and prevent plaque formation in mice.
  • A team from the University of Western Australia found that deposits known as senile plaques seen in the brains of Alzheimer's patients were composed of a new type of protein, which they called beta amyloid.
  • Several types of senile plaques have also been found in the brains of Alzheimer's disease patients, including diffuse, neuritic, and burned out plaques.

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