Definition of Shiga toxin in English:

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Shiga toxin

Pronunciation: /ˈSHēɡə ˌtäksən/


A toxin produced by the bacterium Shigella dysenteriae, or a similar one produced by E. coli, causing dysentery in humans: during infection there are changes of cytokine levels that can be ascribed to an effect of Shiga toxin on different cell types
More example sentences
  • E. coli produces two known toxins called Shiga toxins, which can cause fatal kidney damage.
  • Stec strains carry a set of virulence genes that encode the factors for attachment to host cells, elaboration of effective molecules and production of two different types of Shiga toxins.
  • The assay was based on the incorporation of digoxigenin labeled dUTP and a biotin labeled primer specific for Shiga toxin genes during PCR amplification.


Early 20th century: from the name of Shigella dysenteriae (see also shigella).

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