Definition of sulfasalazine in English:

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Pronunciation: /ˌsəlfəˈsaləzēn/
(chiefly British also sulphasalazine)


A sulfonamide antibiotic used to treat ulcerative colitis and Crohn’s disease.
Example sentences
  • All of the women included in the case part of the study were taking at least one of the following folic acid antagonists: trimethoprim, triamterene, sulfasalazine, phenytoin, phenobarbital, primidone and carbamazepine.
  • At six and 12 months, there was no difference in ACR20 response rate between patients treated with leflunomide and patients treated with sulfasalazine or methotrexate.
  • Almost all sulfonamides are anti-infectives: however, sulfasalazine which is used to treat ulcerative colitis and Crohn's disease, is also included.


Mid 20th century: from sulfa- + sal(icylic acid) + azine.

For editors and proofreaders

Syllabification: sul·fa·sal·a·zine

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