The development of male physical characteristics (such as muscle bulk, body hair, and deep voice) in a female or precociously in a boy, typically as a result of excess androgen production.
- Administration of glucocorticoids inhibits excessive production of androgens, prevents progressive virilization, and stabilizes renin levels.
- Clinical clues to possible hyperandrogenism in women include dysmenorrhea, virilization, and severe acne.
- Patients are often concerned about the physical manifestations of this disorder, including virilization and acanthosis nigricans, and may be less aware of systemic problems.
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