Definition of von Willebrand's disease in English:

von Willebrand's disease

Syllabification: von Wil·le·brand's dis·ease
Pronunciation: /ˌvän ˈviləˌbränts diˌzēz


  • An inherited disorder characterized by a tendency to bleed, caused by deficiency or abnormality of a plasma coagulation factor ( von Willebrand factor).
    More example sentences
    • The most commonly encountered disorders are coagulation factor VIII deficiency, coagulation factor IX deficiency and von Willebrand's disease.
    • Bloat, epilepsy and heart related problems are also reported, as are von Willebrand's disease and hemophilia A.
    • In most patients with von Willebrand disease, factor VIII activity and plasma levels of von Willebrand factor are decreased.


1940s: named after Erik A. von Willebrand (1870–1949), Finnish physician.

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Pronunciation: ˌkələrəˈto͝orə
elaborate ornamentation of a vocal melody