There are 2 definitions of wen in English:

wen1

Syllabification: wen

noun

1A boil or other swelling or growth on the skin, especially a sebaceous cyst.
More example sentences
  • Throughout the sermon that morning, Inman sat staring at Ada's neck and listening as Monroe repeated four times the Emerson passage about warts and wens and decreasing forever.
  • The make-up people excelled themselves with lots of dirty fingernails and a welter of warts, wens and rotten corpses.
  • There was a fellow with a wen in his neck, larger than me, and another with a wooden leg.
1.1 archaic An outstandingly large or overcrowded city: the great wen of London

Origin

Old English wen(n), of unknown origin; compare with Low German wehne 'tumor, wart'.

Definition of wen in:

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Word of the day anomalous
Pronunciation: əˈnämələs
adjective
deviating from what is standard, normal, or expected

There are 2 definitions of wen in English:

wen2

Syllabification: wen

noun

Old-fashioned spelling of wynn.
More example sentences
  • The modern English wine comes from Old English wn, pronounced like modern ‘wean’: that indeed was how Chaucer pronounced his wyn, but Shakespeare's pronunciation was closer to our own.

Definition of wen in: