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Klinefelter's syndrome

Line breaks: Kline|fel¦ter's syn|drome
Pronunciation: /ˈklʌɪnˌfɛltəz
 
/

Definition of Klinefelter's syndrome in English:

noun

[mass noun] Medicine
A syndrome affecting males in which the cells have an extra X chromosome (in addition to the normal XY), characterized by a tall thin physique, small infertile testes, and enlarged breasts.
Example sentences
  • Risk factors for breast cancer in men suggest a hormonal imbalance, and up to 20 percent of male breast cancer cases have been associated with Klinefelter's syndrome.
  • For example, a screening check of Down's Syndrome might pick up the extra X chromosome that occurs in Chris's condition, Klinefelter's syndrome.
  • Men born with a genetic disorder called Klinefelter's syndrome often develop gynecomastia, as do males with adrenal tumors and liver disease.

Origin

1940s: named after Harry F. Klinefelter (born 1912), American physician.

Definition of Klinefelter's syndrome in:

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