Definition of Kupffer cell in English:

Kupffer cell

Line breaks: Kupf|fer cell
Pronunciation: /ˈkʊpfə


  • A phagocytic cell which forms the lining of the sinusoids of the liver and is involved in the breakdown of red blood cells.
    More example sentences
    • Iron deposition in the bile ductal epithelium and Kupffer cells was minimal.
    • It can be identified in canaliculi, in hepatocytes, and in Kupffer cells.
    • Normally, immune complexes are rapidly removed from the bloodstream by macrophages in the spleen, and Kupffer cells in the liver.


early 20th century: named after Karl Wilhelm von Kupffer (1829–1902), Bavarian anatomist.

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