Share this entry

Lesch–Nyhan syndrome Line breaks: Lesch–Nyhan syn|drome
Pronunciation: /lɛʃˈnʌɪhən/

Definition of Lesch–Nyhan syndrome in English:


[mass noun]
A rare hereditary disease which affects young boys, usually causing early death. It is marked by compulsive self-mutilation of the head and hands, together with learning difficulties and involuntary muscular movements.


1960s: named after Michael Lesch (born 1939) and William L. Nyhan (born 1926), American physicians.

Definition of Lesch–Nyhan syndrome in:

Share this entry


What do you find interesting about this word or phrase?

Comments that don't adhere to our Community Guidelines may be moderated or removed.

Get more from Oxford Dictionaries

Subscribe to remove ads and access premium resources