Definition of biguanide in English:
noun[mass noun] Chemistry
A crystalline compound with basic properties, made by condensation of two guanidine molecules.
- Phenformin, another biguanide, was withdrawn from the market after a rate of 40 to 64 cases of lactic acidosis per 100,000 patient-years was reported.
- Metformin is the most common type of biguanide. c.
- Metformin, the only biguanide currently available in the United States, can be used alone or in combination with sulfonylureas.
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