Definition of fibrin in English:

fibrin

Line breaks: fi¦brin
Pronunciation: /ˈfʌɪbrɪn
 
, ˈfɪb-/

noun

[mass noun] Biochemistry
  • An insoluble protein formed from fibrinogen during the clotting of blood. It forms a fibrous mesh that impedes the flow of blood.
    More example sentences
    • Plasminogen binds to both fibrinogen and fibrin, thereby being incorporated into a clot as it is formed.
    • In the assay, the addition of thrombin to citrated plasma causes the conversion of fibrinogen to fibrin, yielding a stops bleeding much quicker.
    • It converts fibrinogen to fibrin, and unlike thrombin, is unaffected by heparin.

Derivatives

fibrinoid

adjective
More example sentences
  • In addition, three patients had hyaline collagen degeneration, four myxoid degeneration, three fibrinoid degeneration, and six had mixed lesions.
  • Fibrin deposition was found in areas of fibrinoid necrosis within the glomeruli and in the interstitium.
  • Other nonspecific features include intimal proliferation, duplication and/or fragmentation of the internal elastic lamina, a sparse perivascular inflammatory infiltrate, and fibrinoid necrosis of the intima.

fibrinous

adjective
More example sentences
  • This progressive process involves alterations in fibrin turnover, which leads to the formation of fibrinous deposits and membranes with sequestration of infected fluid.
  • Upon review of the slides, we observed a fragment of bladder mucosa with dilated vascular spaces, hemorrhage, acute inflammation, fibrinous exudate, and focal fibrosis in the lamina propria.
  • Because the heart is constricted by fluid or a rigid fibrinous or calcified pericardium, negative intrathoracic pressure during inspiration is not transmitted to the pericardial sac.

Origin

early 19th century: from fibre + -in1.

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