Definition of give it one's best shot in English:

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give it one's best shot

informal Do the best that one can: it’s not easy, but I’m going to give it my best shot
More example sentences
  • That's not to say we won't be giving it our best shot.
  • He said: ‘I am giving it my best shot and hoping that we raise as much money as possible so we can help find a cure for Lily quickly.’
  • It will be difficult as there is only a team of three, but I will be giving it my best shot.
See parent entry: shot
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