Three related compounds produced during the metabolism of fats, two of which are used as a source of energy instead of glucose during a period of fasting or very low carbohydrate intake (the third being acetone, which is excreted).
- In the liver the net result (due to increased acetyl-CoA levels) is the production of ketone bodies.
- Glucose is the main fuel used by the brain, but research has shown that neonates are able to use ketone bodies, lactate and maybe amino acids for oxidation.
- Laboratory findings reveal high blood sugar and glucose in the urine and as the metabolic derangement worsens, excessive ketone bodies in the blood and urine.
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