Definition of kinetochore in English:

Share this entry

kinetochore

Pronunciation: /kɪˈniːtəʊkɔː/
/kʌɪˈniːtəʊkɔː/

noun

Biology
1A complex of proteins associated with the centromere of a chromosome during cell division, to which the microtubules of the spindle attach.
1.1 historical another term for centromere.
Example sentences
  • In metaphase, sister kinetochores attach to microtubules emanating from opposite spindle pole bodies during alignment of the chromosomes.
  • Chromosome loss may be the result of either non-attachment of the chromosome kinetochore to the spindle microtubules or chromosome lagging at anaphase and gives rise to a micronucleus.
  • The DNA is asymmetrically distributed to the daughter cells when the kinetochores do not attach and the spindle checkpoint does not restrain mitosis.

Origin

1930s: from kineto- 'of movement' + Greek khōros 'place'.

For editors and proofreaders

Line breaks: kin¦eto|chore

Share this entry
 

What do you find interesting about this word or phrase?

Comments that don't adhere to our Community Guidelines may be moderated or removed.