A phagocytic cell which forms the lining of the sinusoids of the liver and is involved in the breakdown of red blood cells.
- Iron deposition in the bile ductal epithelium and Kupffer cells was minimal.
- It can be identified in canaliculi, in hepatocytes, and in Kupffer cells.
- Normally, immune complexes are rapidly removed from the bloodstream by macrophages in the spleen, and Kupffer cells in the liver.
Early 20th century: named after Karl Wilhelm von Kupffer (1829–1902), Bavarian anatomist.
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