Definition of megaloblast in English:

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Pronunciation: /ˈmɛɡələ(ʊ)blast/


A large, abnormally developed red blood cell typical of certain forms of anaemia, associated with a deficiency of folic acid or of vitamin B12.
Example sentences
  • Enlarged red cells, called megaloblasts, are caused by vitamin B12 deficiency and folate deficiency.
  • Ehrlich distinguished 3 types of granulated white blood cells, as well as normoblasts, megaloblasts, and leukemic cells.
  • Enlarged red cells derived from megaloblasts are a consequence of a deficiency of vitamin B12 or folic acid.



Example sentences
  • Iron-deficiency anaemia and megaloblastic anaemia can occur during pregnancy.
  • The classic affected patient who presents with neuropathy and megaloblastic anemia likely represents the minority of subjects with cobalamin deficiency.
  • Folate and vitamin D deficiency may necessitate vitamin supplementations and, if uncorrected, leads to megaloblastic anemia.

For editors and proofreaders

Line breaks: meg¦alo|blast

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