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melanosis Line breaks: mel¦an|osis
Pronunciation: /ˌmɛləˈnəʊsɪs/

Definition of melanosis in English:


[mass noun] Medicine
A condition of excessive production of melanin in the skin or other tissue.
Example sentences
  • Erythema toxicum neonatorum, transient neonatal pustular melanosis, sucking blister, miliaria, and mongolian spots are among the many benign skin conditions that can occur in newborns.
  • Various types of skin manifestations of arsenic toxicity were observed - from melanosis, keratosis, hyperkeratosis, dorsal keratosis, and nonpitting edema, to gangrene and cancer.
  • A punch biopsy at the border of the lesion is necessary to rule out melanosis secondary to malignant melanoma that manifests as a generalized blue-gray skin discoloration.


Pronunciation: /ˌmɛləˈnɒtɪk/
Example sentences
  • Of the 9 metastatic melanomas, 5 were melanotic and 4 were amelanotic.
  • Therefore, a final diagnosis of melanotic pleomorphic xanthoastrocytoma was made.
  • About 1% of all newborns have a congenital melanotic (black pigmented) nevus or birthmark.


Early 19th century: modern Latin, from Greek melas, melan- 'black' + -osis.

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